BDBM50204290 CHEMBL3979920::US11077111, Compound IIIa::US20230295171, Example 102

SMILES Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12

InChI Key InChIKey=MJHOMTRKVMKCNE-NWDGAFQWSA-N

Data  20 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50204290   

TargetTyrosine-protein kinase(Dog)
Bayer Animal Health

US Patent
LigandPNGBDBM50204290(CHEMBL3979920 | US11077111, Compound IIIa | US2023...)
Affinity DataIC50:  3.07E+3nMAssay Description:A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase(Dog)
Bayer Animal Health

US Patent
LigandPNGBDBM50204290(CHEMBL3979920 | US11077111, Compound IIIa | US2023...)
Affinity DataIC50:  4.83E+3nMAssay Description:A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase(Dog)
Bayer Animal Health

US Patent
LigandPNGBDBM50204290(CHEMBL3979920 | US11077111, Compound IIIa | US2023...)
Affinity DataIC50:  4.62E+3nMAssay Description:A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All...More data for this Ligand-Target Pair